The right choice for you is going to come down to your strategy and how much time you can invest in learning your chosen pairs. I am not of the opinion that a fully technical approach is possible to reach profitability. Fundamentals are always a factor because these are the events that cause people to take action and create the technical signals we see. Learning the fundamentals of one or a handful of currencies, even if you follow multiple pairs including that currency, seems like the better way to gain a winning edge in the markets. There are authors of strategies that claim they can be used on any pair. That may technically be true, but that does not account for the efficiency that strategy may have on a given pair. A scalping strategy may claim to be useful on any pair, but if you take a scalping strategy that is successful on the EURUSD it may fail on the GBPJPY. A scalping strategy that functions on the EURUSD is dealing with a fairly consistent volume and price movements. You could take 5 or 10 pips of profit off of the EURUSD with little trouble. The GBPJPY, on the other hand, is prone to drastic and powerful swings. Going in for 5 or 10 pips is almost a fool's errand because there's no way to cut your stops tight enough to come out ahead. Be certain to research your choice thoroughly and take the time to learn at least some of the basics of the currency. Personally, I keep a separate email account with alerts set to message me news surrounding the Federal Reserve, Bank of Japan, European Central Bank, important economic events, and the big names in the financial sectors. Anyone can do the same with their own choices to provide themselves a platform of potential information for fundamental analysis. Low volume, weaker Exotics are going to suffer from more false signals than pairs like the EURUSD. If you intend to specialize, choose currency pairs that can provide consistency. Look to the Majors or ComDolls for consistency